Engineered chemotaxis core signaling units indicate a constrained kinase-off state
نویسندگان
چکیده
منابع مشابه
Selective allosteric coupling in core chemotaxis signaling complexes.
Bacterial chemotaxis is mediated by signaling complexes that sense chemical gradients and direct bacteria to favorable environments by controlling a histidine kinase as a function of chemoreceptor ligand occupancy. Core signaling complexes contain two trimers of transmembrane chemoreceptor dimers, each trimer binding a coupling protein CheW and a protomer of the kinase dimer. Core complexes ass...
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ژورنال
عنوان ژورنال: Science Signaling
سال: 2020
ISSN: 1945-0877,1937-9145
DOI: 10.1126/scisignal.abc1328